Single-Cell Profiling Services

Elevate Your Single-Cell Analysis — Without the Bench Work

How It Works

Our single-cell services offers a clear time-saving advantage - removing the burdens of specialized training or investment in learning protocols, enabling you to focus on interpretation.

Name Cat. No Price
Single-Cell 3' RNA-Seq SCRS301 Request Quote
Single-Cell ATAC-Seq SCAS302 Request Quote
Single-Cell Multiome ATAC+RNA SCMS303 Request Quote
Additional & Custom Modalities CSS300 Explore

Why Epigenome Technologies?

Protocol Experts: Recognized through high-impact publications and collaborations as pioneers of targeted multi-omics.

Proven Track Record: Hundreds of processed samples of consistently high quality.

Multiple Platforms: Our Single-Cell Services are available for multiple single-cell platforms.

Deep Expertise: Experience with wide variety of tissues and target types, we can ensure your experiment is set up for success.

Single-cell Profiling: Precision 'Omics

IGV of single-cell Paired-Tag PBMC data
  • Whether it's transcriptomics or open chromatin, our services will help you pinpoint cell-specific differences in gene regulation.
  • Platform flexibility: we match platform strength – such as ultra-low cell input, high throughput, or high coverage – to your research needs.
  • These robust methods accept a wide variety of sample types: whole-cell or nuclei; animal, nearly all eukaryotic taxa; fresh or cryopreserved, and even certain degraded samples.

Applications

  1. Cellular Heterogeneity: Dissect complex tissues by revealing cell-specific transcriptomic and chromatin landscapes.
  2. Rare Cell Populations: Detect and characterize elusive cell types or states without the need for extensive sorting.
  3. Biomarkers & Targets: Leverage combined ATAC and RNA profiles to pinpoint gene-regulatory changes that serve as novel therapeutic targets or predictive biomarkers.
  4. Disease Mechanisms: Integrate gene expression with chromatin accessibility data to illuminate molecular drivers in conditions like cancer, autoimmunity, and neurodegeneration.

Comprehensive Services Workflow

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Consultation & Experimental Design

We review your sample types, target histone marks or TFs, and project goals to ensure the optimal protocol is selected.

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Sample Prep & Library Construction

Our highly trained lab technicians handle the full workflow, from nuclei isolation and antibody staining, to single-cell library preparation. Quality control is incorporated into each step to ensure the robust production of ideal libraries. Your libraries can be delivered directly, or sequenced and delivered as sequence reads.

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Sequencing & Data Generation

We partner with leading sequencing providers or work with your preferred facility, guaranteeing high-coverage data.

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Quality Control & Initial Analysis

Our services include basic quality checks, including demultiplexing, alignment, and preliminary clustering, and QC metric generation, delivering data you can readily explore.

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End-to-end Bioinformatics

For labs seeking deeper insights, we offer full downstream analysis—including differential expression, cluster annotation, cis‑regulatory element linking, and integrated RNA+epigenetic visualization—so you can jump straight to biological interpretation.

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Deliverables

  1. Processed fastQ Files Ready for your own pipelines, or integrated with standard tools like CellRanger and provided as Seurat/Scanpy objects.
    Single-Cell Quality Control
  2. Quality Control Reports Overview of library complexity, tagmentation quality, saturation, and cell recovery.
    IGV showing differential abundance in MAIT cells
  3. Optional Bioinformatics Support Additional analysis or custom data visualization can be arranged upon request.
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