Paired-Tag Services
Unlock the Power of Single-Cell Epigenetics - Without the Benchwork
Our Paired-Tag service offers a clear time-saving advantage - removing the burdens of specialized training or investment in learning protocols, enabling you to focus on interpretation.
| Name | Cat. No | Price |
|---|---|---|
| Droplet Paired-Tag | DPS201 | Request Quote |
| Multiplex Droplet Paired-Tag | MDPS201 | Request Quote |
| DamageTag sc-DNA Damage Profiling | DTD201 | Request Quote More Info |
Why Epigenome Technologies?
Protocol Inventors: Recognized through high-impact publications and collaborations as pioneers of targeted multi-omics.
Proven Track Record: Hundreds of processed samples of consistently high quality.
Leading Technology: Our patented Paired-Tag approach is the best-proven method for simultaneous RNA + CUT&Tag profiling.
Deep Expertise: Experience with wide variety of tissues and target types, we can ensure your experiment is set up for success.
Paired-Tag gives the Ultimate Epigenetic Detail
- Paired-Tag combines RNA and CUT&Tag to pinpoint cell-specific regulation even from complex heterogeneous tissues.
- Precise enough to target histone modifications, epigenetic machinery such as PRC, or transcription factors.
- RNA modality lets you link regulatory activity to cell states and even to individual genes.
Applications
- Complex Disease Models: Combine transcriptomics and epigenetics to unravel cancer, autoimmunity, or neurodegeneration.
- Rare Cell Populations: Discover subtle epigenetic variations without expensive sorting.
- Drug Discovery & Validation: Couple histone modification profiles with RNA expression to uncover new therapeutic targets.
- Biomarker Discovery: Identify gene-regulatory changes that correlate with treatment response or resistance.
Comprehensive Services Workflow
Consultation & Experimental Design
We review your sample types, target histone marks or TFs, and project goals to ensure the optimal protocol is selected.
Sample Prep & Library Construction
Our highly trained lab technicians handle the full workflow, from nuclei isolation and antibody staining, to single-cell library preparation. Quality control is incorporated into each step to ensure the robust production of ideal libraries. Your libraries can be delivered directly, or sequenced and delivered as sequence reads.
Sequencing & Data Generation
We partner with leading sequencing providers or work with your preferred facility, guaranteeing high-coverage data.
Quality Control & Initial Analysis
Our services include basic quality checks, including demultiplexing, alignment, and preliminary clustering, and QC metric generation, delivering data you can readily explore.
End-to-end Bioinformatics
For labs seeking deeper insights, we offer full downstream analysis—including differential expression, cluster annotation, cis‑regulatory element linking, and integrated RNA+epigenetic visualization—so you can jump straight to biological interpretation.
Deliverables
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Processed fastQ Files Ready for your own pipelines, or integrated with standard tools like CellRanger and provided as Seurat/Scanpy objects.
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Quality Control Reports Overview of library complexity, tagmentation quality, saturation, and cell recovery.
- Optional Bioinformatics Support Additional analysis or custom data visualization can be arranged upon request.